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Gene: Fpgs (folylpolyglutamate synthase) Rattus norvegicus
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Symbol: Fpgs
Name: folylpolyglutamate synthase
Description: Exhibits tetrahydrofolylpolyglutamate synthase activity. Involved in animal organ regeneration; brain development; and liver development. Predicted to localize to the cytosol and mitochondrion. Orthologous to human FPGS (folylpolyglutamate synthase); PARTICIPATES IN folate cycle metabolic pathway; folate metabolic pathway; hereditary folate malabsorption pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 3,3',5-triiodo-L-thyronine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: folylpolyglutamate synthase, mitochondrial; LOC687266; similar to Folylpolyglutamate synthase, mitochondrial precursor (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase)
Orthologs:
Homo sapiens (human) : FPGS (folylpolyglutamate synthase)  HGNC  Alliance
Mus musculus (house mouse) : Fpgs (folylpolyglutamyl synthetase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fpgs (folylpolyglutamate synthase)
Pan paniscus (bonobo/pygmy chimpanzee) : FPGS (folylpolyglutamate synthase)
Canis lupus familiaris (dog) : FPGS (folylpolyglutamate synthase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fpgs (folylpolyglutamate synthase)
Sus scrofa (pig) : FPGS (folylpolyglutamate synthase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0311,717,667 - 11,729,694 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0317,058,730 - 17,068,957 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera310,713,719 - 10,724,786 (-)NCBICelera
Cytogenetic Map3p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Fpgs
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1587713
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.