Gene: Thbs1 (thrombospondin 1) Rattus norvegicus
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Symbol: Thbs1
Name: thrombospondin 1
Description: Exhibits transforming growth factor beta binding activity; involved in several processes, including cellular response to growth factor stimulus, cellular response to tumor necrosis factor, and negative regulation of angiogenesis; localizes to the cytoplasm and extracellular space; biomarker of diabetic retinopathy, heart disease, myocardial infarction, and prostate cancer; orthologous to human THBS1 (thrombospondin 1); PARTICIPATES IN syndecan signaling pathway; cell-extracellular matrix signaling pathway; malaria pathway; INTERACTS WITH (RS)-amphetamine; (S)-colchicine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: thrombospondin-1; TSP-1; Tsp1
Orthologs:
Homo sapiens (human) : THBS1 (thrombospondin 1)  HGNC  Alliance
Mus musculus (house mouse) : Thbs1 (thrombospondin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Thbs1 (thrombospondin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : THBS1 (thrombospondin 1)
Canis lupus familiaris (dog) : THBS1 (thrombospondin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Thbs1 (thrombospondin 1)
Sus scrofa (pig) : THBS1 (thrombospondin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03109,862,120 - 109,873,466 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03116,411,045 - 116,422,101 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera3103,978,436 - 103,990,486 (+)NCBICelera
Cytogenetic Map3q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Thbs1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1588455
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.