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Gene: Kdm4b (lysine demethylase 4B) Rattus norvegicus
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Symbol: Kdm4b
Name: lysine demethylase 4B
Description: Predicted to have histone demethylase activity (H3-K36 specific) and histone demethylase activity (H3-K9 specific). Predicted to be involved in chromatin organization and negative regulation of histone H3-K9 trimethylation. Localizes to the nucleus. Human ortholog(s) of this gene implicated in breast cancer; colorectal cancer; malignant peripheral nerve sheath tumor; and stomach cancer. Orthologous to human KDM4B (lysine demethylase 4B); PARTICIPATES IN histone modification pathway; INTERACTS WITH bisphenol A; cobalt dichloride; fipronil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC301128; lysine (K)-specific demethylase 4B; lysine-specific demethylase 4B; similar to jumonji domain containing 2B
Orthologs:
Homo sapiens (human) : KDM4B (lysine demethylase 4B)  HGNC  Alliance
Mus musculus (house mouse) : Kdm4b (lysine (K)-specific demethylase 4B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm4b (lysine demethylase 4B)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM4B (lysine demethylase 4B)
Canis lupus familiaris (dog) : KDM4B (lysine demethylase 4B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm4b (lysine demethylase 4B)
Sus scrofa (pig) : KDM4B (lysine demethylase 4B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0910,656,035 - 10,734,127 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.099,647,087 - 9,725,878 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera97,273,613 - 7,351,363 (-)NCBICelera
Cytogenetic Map9q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Kdm4b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1588576
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.