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Gene: Tbk1 (TANK-binding kinase 1) Rattus norvegicus
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Symbol: Tbk1
Name: TANK-binding kinase 1
Description: Predicted to have several functions, including identical protein binding activity; phosphoprotein binding activity; and protein phosphatase binding activity. Predicted to be involved in several processes, including cellular protein modification process; positive regulation of defense response; and positive regulation of type I interferon production. Predicted to localize to the aggresome; cytoplasm; and nucleoplasm. Human ortholog(s) of this gene implicated in FTDALS4 and brain disease. Orthologous to human TBK1 (TANK binding kinase 1); PARTICIPATES IN Toll-like receptor signaling pathway; hepatitis C pathway; influenza A pathway; INTERACTS WITH 3H-1,2-dithiole-3-thione; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC299827; serine/threonine-protein kinase TBK1; similar to TANK-binding kinase 1
Orthologs:
Homo sapiens (human) : TBK1 (TANK binding kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Tbk1 (TANK-binding kinase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbk1 (TANK binding kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TBK1 (TANK binding kinase 1)
Canis lupus familiaris (dog) : TBK1 (TANK binding kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbk1 (TANK binding kinase 1)
Sus scrofa (pig) : TBK1 (TANK binding kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0763,655,247 - 63,687,978 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0763,877,567 - 63,910,298 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4760,863,099 - 60,896,131 (-)NCBIRGSC3.4rn4RGSC3.4
Celera753,819,361 - 53,852,262 (-)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Tbk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1588588
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.