Gene: Nlrp2 (NLR family pyrin domain containing 2) Rattus norvegicus
Symbol: Nlrp2
Name: NLR family pyrin domain containing 2
Description: Predicted to have Pyrin domain binding activity; predicted to be involved in negative regulation of NF-kappaB transcription factor activity, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, and positive regulation of interleukin-1 beta secretion; predicted to colocalize with the nuclear chromosome, telomeric region; orthologous to several human genes including NLRP2 (NLR family pyrin domain containing 2); INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl (ortholog); 2,2',5,5'-tetrachlorobiphenyl (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC684545; NACHT, LRR and PYD domains-containing protein 2; similar to NACHT, leucine rich repeat and PYD containing 2
Homo sapiens (human) : NLRP2 (NLR family pyrin domain containing 2)  HGNC  Alliance
Mus musculus (house mouse) : Nlrp2 (NLR family, pyrin domain containing 2)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : NLRP2 (NLR family pyrin domain containing 2)
Canis lupus familiaris (dog) : NLRP2 (NLR family pyrin domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nlrp2 (NLR family pyrin domain containing 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0173,082,648 - 73,121,118 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0175,425,340 - 75,463,631 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera167,580,163 - 67,618,281 (+)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Nlrp2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1589140
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.