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Gene: Nlrp2 (NLR family pyrin domain containing 2) Rattus norvegicus
Symbol: Nlrp2
Name: NLR family pyrin domain containing 2
Description: Predicted to have Pyrin domain binding activity. Predicted to be involved in negative regulation of NF-kappaB transcription factor activity; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; and positive regulation of interleukin-1 beta secretion. Predicted to colocalize with nuclear chromosome, telomeric region. Orthologous to human NLRP2 (NLR family pyrin domain containing 2); INTERACTS WITH vinclozolin; 2,2',4,4',5,5'-hexachlorobiphenyl (ortholog); 2,2',5,5'-tetrachlorobiphenyl (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC684545; NACHT, LRR and PYD domains-containing protein 2; similar to NACHT, leucine rich repeat and PYD containing 2
Homo sapiens (human) : NLRP2 (NLR family pyrin domain containing 2)  HGNC  Alliance
Mus musculus (house mouse) : Nlrp2 (NLR family, pyrin domain containing 2)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : NLRP2 (NLR family pyrin domain containing 2)
Canis lupus familiaris (dog) : NLRP2 (NLR family pyrin domain containing 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nlrp2 (NLR family pyrin domain containing 2)
Chlorocebus sabaeus (African green monkey) : NLRP2 (NLR family pyrin domain containing 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0173,082,648 - 73,121,118 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl173,082,977 - 73,121,085 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0175,425,340 - 75,463,631 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera167,580,163 - 67,618,281 (+)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Nlrp2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1589140
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.