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Gene: F5 (coagulation factor V) Rattus norvegicus
Symbol: F5
Name: coagulation factor V
Description: Predicted to have ferroxidase activity. Involved in blood coagulation and response to vitamin K. Localizes to Golgi apparatus; endoplasmic reticulum; and extracellular space. Used to study membranoproliferative glomerulonephritis. Biomarker of colon adenoma; hepatitis; and portal hypertension. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); end stage renal disease; factor V deficiency; liver disease (multiple); and non-arteritic anterior ischemic optic neuropathy. Orthologous to human F5 (coagulation factor V); PARTICIPATES IN coagulation cascade pathway; acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
Also known as: Ac2-120; coagulation factor 5; coagulation factor 5 (mapped); coagulation factor V (proaccelerin, labile factor); F5_mapped
Homo sapiens (human) : F5 (coagulation factor V)  HGNC  Alliance
Mus musculus (house mouse) : F5 (coagulation factor V)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : F5 (coagulation factor V)
Pan paniscus (bonobo/pygmy chimpanzee) : F5 (coagulation factor V)
Canis lupus familiaris (dog) : F5 (coagulation factor V)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : F5 (coagulation factor V)
Sus scrofa (pig) : F5 (coagulation factor V)
Chlorocebus sabaeus (African green monkey) : F5 (coagulation factor V)
Heterocephalus glaber (naked mole-rat) : F5 (coagulation factor V)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01382,479,997 - 82,535,540 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1382,479,998 - 82,535,534 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01387,355,980 - 87,417,686 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41379,934,956 - 79,997,285 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1376,256,969 - 76,316,731 (+)NCBICelera
Cytogenetic Map13q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on F5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1589758
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.