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Gene: Mcu (mitochondrial calcium uniporter) Rattus norvegicus
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Symbol: Mcu
Name: mitochondrial calcium uniporter
Description: Exhibits uniporter activity. Involved in mitochondrial calcium ion transmembrane transport and positive regulation of mitochondrial calcium ion concentration. Localizes to the mitochondrial inner membrane. Orthologous to human MCU (mitochondrial calcium uniporter); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH bisphenol A; Brodifacoum; ketamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: calcium uniporter protein, mitochondrial; Ccdc109a; coiled-coil domain containing 109A; coiled-coil domain-containing protein 109A; LOC294560; similar to CG18769-PB, isoform B
Orthologs:
Homo sapiens (human) : MCU (mitochondrial calcium uniporter)  HGNC  Alliance
Mus musculus (house mouse) : Mcu (mitochondrial calcium uniporter)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mcu (mitochondrial calcium uniporter)
Pan paniscus (bonobo/pygmy chimpanzee) : MCU (mitochondrial calcium uniporter)
Canis lupus familiaris (dog) : MCU (mitochondrial calcium uniporter)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mcu (mitochondrial calcium uniporter)
Sus scrofa (pig) : MCU (mitochondrial calcium uniporter)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02029,037,452 - 29,199,224 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02030,840,963 - 31,003,860 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2028,862,404 - 29,023,532 (-)NCBICelera
Cytogenetic Map20q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mcu
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1589771
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.