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Gene: Vps35 (VPS35 retromer complex component) Rattus norvegicus
Symbol: Vps35
Name: VPS35 retromer complex component
CRRD ID: 1589784
Description: Predicted to have D1 dopamine receptor binding activity. Involved in retrograde transport, endosome to Golgi. Localizes to cytosol and retromer complex. Predicted to colocalize with mitochondrion. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 17. Orthologous to human VPS35 (VPS35 retromer complex component); PARTICIPATES IN altered retromer-mediated pathway; Parkinson's disease pathway; retromer-mediated pathway; INTERACTS WITH benzo[a]pyrene; bisphenol A; finasteride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Maternal embryonic message 3; Mem3; vacuolar protein sorting 35; vacuolar protein sorting 35 (mapped); vacuolar protein sorting 35 homolog; vacuolar protein sorting 35 homolog (S. cerevisiae); vacuolar protein sorting-associated protein 35; Vps35_mapped
Homo sapiens (human) : VPS35 (VPS35 retromer complex component)  HGNC  Alliance
Mus musculus (house mouse) : Vps35 (VPS35 retromer complex component)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Vps35 (VPS35 retromer complex component)
Pan paniscus (bonobo/pygmy chimpanzee) : VPS35 (VPS35 retromer complex component)
Canis lupus familiaris (dog) : VPS35 (VPS35 retromer complex component)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Vps35 (VPS35 retromer complex component)
Sus scrofa (pig) : VPS35 (VPS35 retromer complex component)
Chlorocebus sabaeus (African green monkey) : VPS35 (VPS35 retromer complex component)
Heterocephalus glaber (naked mole-rat) : Vps35 (VPS35 retromer complex component)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01927,464,937 - 27,500,636 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1927,464,937 - 27,500,636 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01938,430,733 - 38,466,263 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41923,124,790 - 23,161,655 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1921,625,446 - 21,661,413 (+)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Vps35
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1589784
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.