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Gene: Tnfsf8 (TNF superfamily member 8) Rattus norvegicus
Symbol: Tnfsf8
Name: TNF superfamily member 8
Description: Predicted to have tumor necrosis factor receptor binding activity. Predicted to be involved in CD8-positive, alpha-beta T cell differentiation; defense response to Gram-positive bacterium; and positive regulation of transcription by RNA polymerase II. Predicted to localize to integral component of membrane. Orthologous to human TNFSF8 (TNF superfamily member 8); PARTICIPATES IN cytokine mediated signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
Also known as: CD30 antigen ligand; LOC683163; similar to Tumor necrosis factor ligand superfamily member 8 (CD30 ligand) (CD30-L) (CD153 antigen); Tnlg3a; tumor necrosis factor (ligand) superfamily, member 8; tumor necrosis factor ligand 3a; tumor necrosis factor ligand superfamily member 8; tumor necrosis factor superfamily member 8
Homo sapiens (human) : TNFSF8 (TNF superfamily member 8)  HGNC  Alliance
Mus musculus (house mouse) : Tnfsf8 (tumor necrosis factor (ligand) superfamily, member 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnfsf8 (TNF superfamily member 8)
Pan paniscus (bonobo/pygmy chimpanzee) : TNFSF8 (TNF superfamily member 8)
Canis lupus familiaris (dog) : TNFSF8 (TNF superfamily member 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnfsf8 (TNF superfamily member 8)
Sus scrofa (pig) : TNFSF8 (TNF superfamily member 8)
Chlorocebus sabaeus (African green monkey) : TNFSF8 (TNF superfamily member 8)
Heterocephalus glaber (naked mole-rat) : Tnfsf8 (TNF superfamily member 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0579,664,779 - 79,691,547 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl579,664,765 - 79,691,258 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0583,767,957 - 83,794,108 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera576,184,919 - 76,207,847 (-)NCBICelera
Cytogenetic Map5q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Tnfsf8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1590403
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.