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Gene: Cdc45 (cell division cycle 45) Rattus norvegicus
Symbol: Cdc45
Name: cell division cycle 45
CRRD ID: 1590928
Description: Predicted to have DNA replication origin binding activity; chromatin binding activity; and single-stranded DNA binding activity. Predicted to be involved in several processes, including DNA-dependent DNA replication; double-strand break repair via break-induced replication; and positive regulation of G1/S transition of mitotic cell cycle. Predicted to localize to microtubule organizing center and nucleoplasm. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 7. Orthologous to human CDC45 (cell division cycle 45); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
Also known as: CDC45 cell division cycle 45-like; CDC45 cell division cycle 45-like (S. cerevisiae); CDC45-related protein; Cdc45l; cell division control protein 45 homolog; cell division cycle 45 homolog; cell division cycle 45 homolog (S. cerevisiae); cell division cycle 45 homolog (S. cerevisiae)-like; cell division cycle 45 homolog-like; LOC287961; similar to cell division cycle 45 homolog (S. cerevisiae)-like
Homo sapiens (human) : CDC45 (cell division cycle 45)  HGNC  Alliance
Mus musculus (house mouse) : Cdc45 (cell division cycle 45)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdc45 (cell division cycle 45)
Pan paniscus (bonobo/pygmy chimpanzee) : CDC45 (cell division cycle 45)
Canis lupus familiaris (dog) : CDC45 (cell division cycle 45)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdc45 (cell division cycle 45)
Sus scrofa (pig) : CDC45 (cell division cycle 45)
Chlorocebus sabaeus (African green monkey) : CDC45 (cell division cycle 45)
Heterocephalus glaber (naked mole-rat) : Cdc45 (cell division cycle 45)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01186,328,785 - 86,354,099 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1186,329,012 - 86,358,453 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01189,431,161 - 89,456,065 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1180,966,334 - 80,990,943 (+)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Cdc45
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1590928
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.