Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Sgsh (N-sulfoglucosamine sulfohydrolase) Rattus norvegicus
Symbol: Sgsh
Name: N-sulfoglucosamine sulfohydrolase
Description: Predicted to have N-acetylglucosamine-6-sulfatase activity; N-sulfoglucosamine sulfohydrolase activity; and glycosaminoglycan binding activity. Predicted to be involved in glycosaminoglycan catabolic process and heparan sulfate proteoglycan catabolic process. Predicted to localize to lysosome. Human ortholog(s) of this gene implicated in mucopolysaccharidosis III and mucopolysaccharidosis type IIIA. Orthologous to human SGSH (N-sulfoglucosamine sulfohydrolase); INTERACTS WITH 1,2-dimethylhydrazine (ortholog); 17beta-estradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC688293; N-sulphoglucosamine sulphohydrolase; similar to N-sulfoglucosamine sulfohydrolase (sulfamidase)
Homo sapiens (human) : SGSH (N-sulfoglucosamine sulfohydrolase)  HGNC  Alliance
Mus musculus (house mouse) : Sgsh (N-sulfoglucosamine sulfohydrolase (sulfamidase))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sgsh (N-sulfoglucosamine sulfohydrolase)
Pan paniscus (bonobo/pygmy chimpanzee) : SGSH (N-sulfoglucosamine sulfohydrolase)
Canis lupus familiaris (dog) : SGSH (N-sulfoglucosamine sulfohydrolase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sgsh (N-sulfoglucosamine sulfohydrolase)
Sus scrofa (pig) : SGSH (N-sulfoglucosamine sulfohydrolase)
Chlorocebus sabaeus (African green monkey) : SGSH (N-sulfoglucosamine sulfohydrolase)
Heterocephalus glaber (naked mole-rat) : Sgsh (N-sulfoglucosamine sulfohydrolase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.010108,469,312 - 108,479,094 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010108,075,298 - 108,085,523 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera10103,150,568 - 103,160,450 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Sgsh
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1591134
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.