Gene: Tmc8 (transmembrane channel-like 8) Rattus norvegicus
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Symbol: Tmc8
Name: transmembrane channel-like 8
Description: Predicted to have ion channel activity, mechanosensitive ion channel activity, and signaling receptor binding activity; predicted to be involved in several processes, including negative regulation of protein binding activity, negative regulation of protein oligomerization, and regulation of cell growth; predicted to localize to the Golgi apparatus, endoplasmic reticulum, and nuclear membrane; orthologous to human TMC8 (transmembrane channel like 8); INTERACTS WITH bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog); antirheumatic drug (ortholog).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: hypothetical protein LOC688276; LOC688276; similar to epidermodysplasia verruciformis 2; transmembrane channel-like protein 8; uncharacterized protein LOC688276
Orthologs:
Homo sapiens (human) : TMC8 (transmembrane channel like 8)  HGNC  Alliance
Mus musculus (house mouse) : Tmc8 (transmembrane channel-like gene family 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmc8 (transmembrane channel like 8)
Pan paniscus (bonobo/pygmy chimpanzee) : TMC8 (transmembrane channel like 8)
Canis lupus familiaris (dog) : TMC8 (transmembrane channel like 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmc8 (transmembrane channel like 8)
Sus scrofa (pig) : TMC8 (transmembrane channel like 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.010106,784,819 - 106,795,307 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010106,422,924 - 106,433,661 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera10101,561,134 - 101,571,408 (+)NCBICelera
Cytogenetic Map10q32.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Tmc8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1591150
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.