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Gene: Tbr1 (T-box brain transcription factor 1) Rattus norvegicus
Symbol: Tbr1
Name: T-box brain transcription factor 1
Description: Exhibits protein kinase binding activity. Involved in cerebral cortex development. Localizes to nucleus. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human TBR1 (T-box brain transcription factor 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC680427; similar to T-box brain gene 1; T-box brain gene 1; T-box brain protein 1; T-box, brain, 1; T-box, brain, 1-like
Homo sapiens (human) : TBR1 (T-box brain transcription factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Tbr1 (T-box brain transcription factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tbr1 (T-box brain transcription factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TBR1 (T-box brain transcription factor 1)
Canis lupus familiaris (dog) : TBR1 (T-box brain transcription factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tbr1 (T-box brain transcription factor 1)
Sus scrofa (pig) : TBR1 (T-box brain transcription factor 1)
Chlorocebus sabaeus (African green monkey) : TBR1 (T-box brain transcription factor 1)
Heterocephalus glaber (naked mole-rat) : Tbr1 (T-box brain transcription factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0347,677,720 - 47,685,902 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl347,677,720 - 47,685,902 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0354,349,276 - 54,356,654 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4343,647,046 - 43,655,746 (-)NCBIRGSC3.4rn4RGSC3.4
Celera346,019,111 - 46,026,902 (+)NCBICelera
Cytogenetic Map3q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Tbr1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1591773
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.