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Gene: Pappa2 (pappalysin 2) Rattus norvegicus
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Symbol: Pappa2
Name: pappalysin 2
Description: Predicted to have metallopeptidase activity. Involved in response to salt stress. Localizes to the apical plasma membrane and cytosol. Orthologous to human PAPPA2 (pappalysin 2); INTERACTS WITH bisphenol A; aflatoxin B1 (ortholog); all-trans-retinoic acid (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC680069; LOC680415; pappalysin-2; similar to pappalysin 2 isoform 1; similar to Pappalysin-2 precursor (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP-E)
Orthologs:
Homo sapiens (human) : PAPPA2 (pappalysin 2)  HGNC  Alliance
Mus musculus (house mouse) : Pappa2 (pappalysin 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pappa2 (pappalysin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PAPPA2 (pappalysin 2)
Canis lupus familiaris (dog) : PAPPA2 (pappalysin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pappa2 (pappalysin 2)
Sus scrofa (pig) : PAPPA2 (pappalysin 2)
more info ...
Allele / Splice: Pappa2em4Mcwi   Pappa2em5Mcwi  
Genetic Models: SS.BN-(D13Hmgc1048-D13Hmgc1050)-Pappa2em4Mcwi SS.BN-(D13Hmgc1048-D13Hmgc1050)-Pappa2em5Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01376,389,150 - 76,660,248 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01381,303,663 - 81,574,402 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41374,286,881 - 74,379,736 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1370,687,413 - 70,959,267 (-)NCBICelera
Cytogenetic Map13q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Pappa2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1591785
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.