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Gene: Sox3 (SRY-box transcription factor 3) Rattus norvegicus
Symbol: Sox3
Name: SRY-box transcription factor 3
Description: Predicted to have RNA polymerase II core promoter sequence-specific DNA binding activity and transcription corepressor activity. Predicted to be involved in several processes, including animal organ development; face development; and spermatid differentiation. Predicted to localize to nucleoplasm. Human ortholog(s) of this gene implicated in X-linked panhypopituitarism. Orthologous to human SOX3 (SRY-box transcription factor 3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; (+)-catechin (ortholog); 17beta-estradiol (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC679158; LOW QUALITY PROTEIN: transcription factor SOX-3; similar to SRY (sex determining region Y)-box 3; SRY-box 3; SRY-box containing gene 3; transcription factor SOX-3
Homo sapiens (human) : SOX3 (SRY-box transcription factor 3)  HGNC  Alliance
Mus musculus (house mouse) : Sox3 (SRY (sex determining region Y)-box 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sox3 (SRY-box transcription factor 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SOX3 (SRY-box transcription factor 3)
Canis lupus familiaris (dog) : SOX3 (SRY-box transcription factor 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sox3 (SRY-box transcription factor 3)
Sus scrofa (pig) : SOX3 (SRY-box transcription factor 3)
Chlorocebus sabaeus (African green monkey) : SOX3 (SRY-box transcription factor 3)
Heterocephalus glaber (naked mole-rat) : Sox3 (SRY-box transcription factor 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X144,035,162 - 144,037,364 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX144,035,883 - 144,037,294 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X144,060,911 - 144,062,696 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X146,510,409 - 146,511,936 (-)NCBIRGSC3.4rn4RGSC3.4
CeleraX135,369,404 - 135,371,527 (-)NCBICelera
Cytogenetic MapXq36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Sox3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1591839
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.