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Gene: C4b (complement C4B (Chido blood group)) Rattus norvegicus
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Symbol: C4b
Name: complement C4B (Chido blood group)
Description: Predicted to have carbohydrate binding activity and complement component C1q binding activity. Predicted to be involved in several processes, including complement activation; detection of molecule of bacterial origin; and positive regulation of apoptotic cell clearance. Localizes to the extracellular space. Human ortholog(s) of this gene implicated in autistic disorder; autoimmune hypersensitivity disease (multiple); complement deficiency (multiple); renal cell carcinoma; and rheumatoid arthritis. Orthologous to several human genes including C4B (complement C4B (Chido blood group)); PARTICIPATES IN coagulation cascade pathway; complement system pathway; Staphylococcus aureus infection pathway; INTERACTS WITH 17alpha-ethynylestradiol; 3,3',5,5'-tetrabromobisphenol A; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C4-2; C4l; complement C4-like protein; complement component 4, gene 2; complement component 4B (Chido blood group)
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0204,302,344 - 4,316,752 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,302,344 - 4,316,715 (-)Ensembl
Rnor_5.0206,381,700 - 6,396,108 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,300,687 - 4,315,882 (+)NCBIRGSC3.4rn4RGSC3.4
Celera203,819,383 - 3,833,684 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on C4b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1591983
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.