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Gene: Siah3 (siah E3 ubiquitin protein ligase family member 3) Rattus norvegicus
Symbol: Siah3
Name: siah E3 ubiquitin protein ligase family member 3
Description: Predicted to have ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Predicted to be involved in negative regulation of protein targeting to mitochondrion; proteasome-mediated ubiquitin-dependent protein catabolic process; and regulation of protein stability. Predicted to localize to the mitochondrion. Orthologous to human SIAH3 (siah E3 ubiquitin protein ligase family member 3); INTERACTS WITH bisphenol A; aflatoxin B1 (ortholog); aflatoxin B2 (ortholog).
Type: protein-coding
RefSeq Status: INFERRED
Also known as: LOC692004; seven in absentia homolog 3; seven in absentia homolog 3 (Drosophila); seven in absentia homolog 3-like; similar to Ubiquitin ligase Siah2 (Seven in absentia homolog 2-like) (Siah-2)
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01557,505,449 - 57,568,743 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01561,215,305 - 61,278,376 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41556,320,672 - 56,387,549 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1550,401,567 - 50,465,060 (+)NCBICelera
Cytogenetic Map15q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Siah3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1592168
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.