Gene: Mt2A (metallothionein 2A) Rattus norvegicus
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Symbol: Mt2A
Name: metallothionein 2A
Description: Exhibits cadmium ion binding activity and zinc ion binding activity; involved in astrocyte activation; predicted to localize to the nucleus and perinuclear region of cytoplasm; biomarker of Alzheimer's disease, kidney failure, median neuropathy, retinitis pigmentosa, and transient cerebral ischemia; orthologous to several human genes including MT1X (metallothionein 1X) and MT2A (metallothionein 2A); INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC689415; Mt2; similar to Metallothionein-2 (MT-2) (Metallothionein-II) (MT-II)
Orthologs:
Homo sapiens (human) : MT2A (metallothionein 2A)  HGNC  Alliance
Mus musculus (house mouse) : Mt2 (metallothionein 2)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100986475 (metallothionein-2)
Canis lupus familiaris (dog) : MT2A (metallothionein 1H)
Sus scrofa (pig) : MT-2B (metallothionein-2A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01911,307,966 - 11,308,740 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01911,283,093 - 11,283,867 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41911,267,811 - 11,268,585 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1910,717,971 - 10,718,745 (-)NCBICelera
Cytogenetic Map19p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mt2A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1592345
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.