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Gene: Isx (intestine-specific homeobox) Rattus norvegicus
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Symbol: Isx
Name: intestine-specific homeobox
CRRD ID: 1592776
Description: Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of intestinal absorption; regulation of transcription by RNA polymerase II; and regulation of vitamin A metabolic process. Predicted to localize to nucleus. Orthologous to human ISX (intestine specific homeobox); INTERACTS WITH bisphenol A; 1,2-dimethylhydrazine (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC682968; similar to Retinal homeobox protein Rx (DRx1) (DRx)
Orthologs:
Homo sapiens (human) : ISX (intestine specific homeobox)  HGNC  Alliance
Mus musculus (house mouse) : Isx (intestine specific homeobox)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Isx (intestine specific homeobox)
Pan paniscus (bonobo/pygmy chimpanzee) : ISX (intestine specific homeobox)
Canis lupus familiaris (dog) : ISX (intestine specific homeobox)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Isx (intestine specific homeobox)
Sus scrofa (pig) : ISX (intestine specific homeobox)
Chlorocebus sabaeus (African green monkey) : ISX (intestine specific homeobox)
Heterocephalus glaber (naked mole-rat) : Isx (intestine specific homeobox)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01914,198,899 - 14,219,269 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1914,198,899 - 14,218,531 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01925,312,031 - 25,333,241 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1913,089,232 - 13,110,157 (+)NCBICelera
Cytogenetic Map19p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Isx
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1592776
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.