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Gene: Rbpj (recombination signal binding protein for immunoglobulin kappa J region) Rattus norvegicus
Symbol: Rbpj
Name: recombination signal binding protein for immunoglobulin kappa J region
Description: Predicted to have several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II repressing transcription factor binding activity; and protein N-terminus binding activity. Involved in several processes, including negative regulation of smooth muscle cell apoptotic process; negative regulation of smooth muscle cell migration; and positive regulation of smooth muscle cell proliferation. Localizes to nucleus and protein-DNA complex. Human ortholog(s) of this gene implicated in Adams-Oliver syndrome and dilated cardiomyopathy. Orthologous to human RBPJ (recombination signal binding protein for immunoglobulin kappa J region); PARTICIPATES IN Notch signaling pathway; Notch signaling pathway; Notch signaling pathway; INTERACTS WITH acrylamide; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: INFERRED
Also known as: LOC679028; recombining binding protein suppressor of hairless; similar to Recombining binding protein suppressor of hairless (J kappa-recombination signal binding protein) (RBP-J kappa)
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01459,657,738 - 59,865,427 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1459,658,935 - 59,735,450 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01459,785,053 - 59,859,229 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1456,447,546 - 56,510,235 (-)NCBICelera
Cytogenetic Map14q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Rbpj
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1593096
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.