Gene: Eng (endoglin) Rattus norvegicus
Analyze
Symbol: Eng
Name: endoglin
Description: Exhibits type II transforming growth factor beta receptor binding activity; predicted to contribute to BMP binding activity; involved in several processes, including bone development, cellular response to mechanical stimulus, and positive regulation of macromolecule metabolic process; localizes to the cell surface and extracellular space; used to study congestive heart failure, pre-eclampsia, and renal fibrosis; biomarker of cholestasis, congestive heart failure, hepatocellular carcinoma, hypertension (multiple), and renal fibrosis; orthologous to human ENG (endoglin); PARTICIPATES IN hypoxia inducible factor pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC124909
Orthologs:
Homo sapiens (human) : ENG (endoglin)  HGNC  Alliance
Mus musculus (house mouse) : Eng (endoglin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Eng (endoglin)
Pan paniscus (bonobo/pygmy chimpanzee) : ENG (endoglin)
Canis lupus familiaris (dog) : ENG (endoglin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Eng (endoglin)
Sus scrofa (pig) : ENG (endoglin)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0311,679,530 - 11,717,486 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0317,021,673 - 17,058,548 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera310,675,660 - 10,713,537 (+)NCBICelera
Cytogenetic Map3p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Eng
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1593188
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.