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Gene: Iqsec3 (IQ motif and Sec7 domain ArfGEF 3) Rattus norvegicus
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Symbol: Iqsec3
Name: IQ motif and Sec7 domain ArfGEF 3
Description: Predicted to have ARF guanyl-nucleotide exchange factor activity. Involved in activation of GTPase activity; regulation of small GTPase mediated signal transduction; and synapse organization. Localizes to the GABA-ergic synapse. Orthologous to human IQSEC3 (IQ motif and Sec7 domain 3); PARTICIPATES IN endocytosis pathway; INTERACTS WITH (RS)-amphetamine; acrylamide; atrazine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: IQ motif and Sec7 domain 3; IQ motif and SEC7 domain-containing protein 3; potential synaptic guanine nucleotide exchange factor for Arf; sag; synArfGEF; synArfGEF-Po
Orthologs:
Homo sapiens (human) : IQSEC3 (IQ motif and Sec7 domain ArfGEF 3)  HGNC  Alliance
Mus musculus (house mouse) : Iqsec3 (IQ motif and Sec7 domain 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Iqsec3 (IQ motif and Sec7 domain ArfGEF 3)
Pan paniscus (bonobo/pygmy chimpanzee) : IQSEC3 (IQ motif and Sec7 domain ArfGEF 3)
Canis lupus familiaris (dog) : IQSEC3 (IQ motif and Sec7 domain 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Iqsec3 (IQ motif and Sec7 domain ArfGEF 3)
Sus scrofa (pig) : IQSEC3 (IQ motif and Sec7 domain ArfGEF 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04153,948,052 - 154,044,493 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04221,035,992 - 221,132,460 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44157,807,767 - 157,904,039 (-)NCBIRGSC3.4rn4RGSC3.4
Celera4143,449,428 - 143,544,902 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Iqsec3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1593191
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-09-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.