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Gene: Iqsec3 (IQ motif and Sec7 domain ArfGEF 3) Rattus norvegicus
Symbol: Iqsec3
Name: IQ motif and Sec7 domain ArfGEF 3
Description: Predicted to have ARF guanyl-nucleotide exchange factor activity. Involved in activation of GTPase activity; regulation of small GTPase mediated signal transduction; and synapse organization. Localizes to the GABA-ergic synapse. Orthologous to human IQSEC3 (IQ motif and Sec7 domain 3); PARTICIPATES IN endocytosis pathway; INTERACTS WITH (RS)-amphetamine; acrylamide; atrazine.
Type: protein-coding
Also known as: IQ motif and Sec7 domain 3; IQ motif and SEC7 domain-containing protein 3; potential synaptic guanine nucleotide exchange factor for Arf; sag; synArfGEF; synArfGEF-Po
Homo sapiens (human) : IQSEC3 (IQ motif and Sec7 domain ArfGEF 3)  HGNC  Alliance
Mus musculus (house mouse) : Iqsec3 (IQ motif and Sec7 domain 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Iqsec3 (IQ motif and Sec7 domain ArfGEF 3)
Pan paniscus (bonobo/pygmy chimpanzee) : IQSEC3 (IQ motif and Sec7 domain ArfGEF 3)
Canis lupus familiaris (dog) : IQSEC3 (IQ motif and Sec7 domain 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Iqsec3 (IQ motif and Sec7 domain ArfGEF 3)
Sus scrofa (pig) : IQSEC3 (IQ motif and Sec7 domain ArfGEF 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04153,948,052 - 154,044,493 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04221,035,992 - 221,132,460 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44157,807,767 - 157,904,039 (-)NCBIRGSC3.4rn4RGSC3.4
Celera4143,449,428 - 143,544,902 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Iqsec3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1593191
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-09-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.