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Gene: Tyrp1 (tyrosinase-related protein 1) Rattus norvegicus
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Symbol: Tyrp1
Name: tyrosinase-related protein 1
Description: Predicted to have monophenol monooxygenase activity; protein heterodimerization activity; and protein homodimerization activity. Predicted to be involved in several processes, including acetoacetic acid metabolic process; melanosome organization; and positive regulation of melanin biosynthetic process. Predicted to localize to clathrin-coated endocytic vesicle membrane; endosome membrane; and melanosome membrane. Human ortholog(s) of this gene implicated in oculocutaneous albinism; oculocutaneous albinism type III; and pigmentation disease. Orthologous to human TYRP1 (tyrosinase related protein 1); PARTICIPATES IN tyrosine metabolic pathway; INTERACTS WITH bisphenol A; cocaine; decabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 5,6-dihydroxyindole-2-carboxylic acid oxidase; B; tyrosinase-related protein 1 (mapped); tyrosine phosphatase 1, same as B (Brown); Tyrp1_mapped
Orthologs:
Homo sapiens (human) : TYRP1 (tyrosinase related protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Tyrp1 (tyrosinase-related protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tyrp1 (tyrosinase related protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TYRP1 (tyrosinase related protein 1)
Canis lupus familiaris (dog) : TYRP1 (tyrosinase related protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tyrp1 (tyrosinase related protein 1)
Sus scrofa (pig) : TYRP1 (tyrosinase related protein 1)
Chlorocebus sabaeus (African green monkey) : TYRP1 (tyrosinase related protein 1)
Heterocephalus glaber (naked mole-rat) : Tyrp1 (tyrosinase related protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0598,387,291 - 98,406,083 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl598,387,291 - 98,406,083 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05102,430,674 - 102,449,645 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4599,518,306 - 99,537,289 (+)NCBIRGSC3.4rn4RGSC3.4
Celera593,854,189 - 93,872,732 (+)NCBICelera
Cytogenetic Map5q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tyrp1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1593266
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-03-31
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.