Gene: RT1-Da (RT1 class II, locus Da) Rattus norvegicus
Symbol: RT1-Da
Name: RT1 class II, locus Da
Description: Predicted to have peptide antigen binding activity; predicted to be involved in cognition, peptide antigen assembly with MHC class II protein complex, and polysaccharide assembly with MHC class II protein complex; predicted to localize to the MHC class II protein complex, cell surface, and cytoplasm; biomarker of prediabetes syndrome; orthologous to human HLA-DRA (major histocompatibility complex, class II, DR alpha); PARTICIPATES IN interleukin-12 signaling pathway; allograft rejection pathway; antigen processing and presentation pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2,4-trimethylbenzene; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DA1; H2-Ea; histocompatibility 2, class II antigen E alpha; MGC112637; MHC class II antigen RT1.D alpha chain; MHC class II RT1D alpha chain antigen; MHC RT1.u-D-alpha chain; RT1 class II, locus Da (mapped); RT1-D alpha; RT1-Da_mapped; RT1-Daa; RT1-Dab; RT1-Dac; RT1-Dad; RT1-Daf; RT1-Dah; RT1-Dak; RT1-Dal; RT1-Dam; RT1-Dan; RT1-Du alpha; RT1-u
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0204,127,644 - 4,132,616 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0206,207,782 - 6,212,754 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,636,310 - 4,641,282 (+)NCBIRGSC3.4rn4RGSC3.4
Celera206,115,646 - 6,120,618 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on RT1-Da
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1593283
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.