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Gene: Diaph3 (diaphanous-related formin 3) Rattus norvegicus
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Symbol: Diaph3
Name: diaphanous-related formin 3
Description: Predicted to have Rho GTPase binding activity and actin binding activity. Involved in spermatogenesis. Localizes to the cytoplasm and nucleus. Human ortholog(s) of this gene implicated in autosomal dominant auditory neuropathy 1. Orthologous to human DIAPH3 (diaphanous related formin 3); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Diap3; diaphanous homolog 3; diaphanous homolog 3 (Drosophila); DRF3; LOC290396; mDIA2; similar to Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2)
Orthologs:
Homo sapiens (human) : DIAPH3 (diaphanous related formin 3)  HGNC  Alliance
Mus musculus (house mouse) : Diaph3 (diaphanous related formin 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Diaph3 (diaphanous related formin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : DIAPH3 (diaphanous related formin 3)
Canis lupus familiaris (dog) : DIAPH3 (diaphanous related formin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Diaph3 (diaphanous related formin 3)
Sus scrofa (pig) : DIAPH3 (diaphanous related formin 3)
more info ...
Allele / Splice: Diaph3Tn(sb-T2/Bart3)2.318Mcwi  
Genetic Models: F344-Diaph3Tn(sb-T2/Bart3)2.318Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01569,928,507 - 70,400,077 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01573,538,942 - 74,007,617 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41568,905,784 - 69,267,707 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1562,058,201 - 62,525,728 (-)NCBICelera
Cytogenetic Map15q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Diaph3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1593287
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.