Gene: Suz12 (SUZ12 polycomb repressive complex 2 subunit) Rattus norvegicus
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Symbol: Suz12
Name: SUZ12 polycomb repressive complex 2 subunit
Description: Predicted to contribute to histone methyltransferase activity (H3-K27 specific); involved in several processes, including histone H3-K27 trimethylation, negative regulation of chemokine production, and negative regulation of epithelial cell proliferation; predicted to localize to several cellular components, including the intracellular organelle and protein-DNA complex; biomarker of spina bifida; orthologous to human SUZ12 (SUZ12 polycomb repressive complex 2 subunit); PARTICIPATES IN histone modification pathway; INTERACTS WITH morphine; (-)-demecolcine (ortholog); 1,4-dichlorobenzene (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC688041; polycomb protein SUZ12; similar to Polycomb protein Suz12 (Suppressor of zeste 12 protein homolog)
Orthologs:
Homo sapiens (human) : SUZ12 (SUZ12 polycomb repressive complex 2 subunit)  HGNC  Alliance
Mus musculus (house mouse) : Suz12 (SUZ12 polycomb repressive complex 2 subunit)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Suz12 (SUZ12 polycomb repressive complex 2 subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : SUZ12 (SUZ12 polycomb repressive complex 2 subunit)
Canis lupus familiaris (dog) : SUZ12 (SUZ12 polycomb repressive complex 2 subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Suz12 (SUZ12 polycomb repressive complex 2 subunit)
Sus scrofa (pig) : SUZ12 (SUZ12 polycomb repressive complex 2 subunit)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01067,325,101 - 67,371,588 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01066,983,892 - 67,031,108 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1063,933,379 - 63,979,240 (+)NCBICelera
Cytogenetic Map10q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Suz12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1593621
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.