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Gene: Tdgf1 (teratocarcinoma-derived growth factor 1) Rattus norvegicus
Symbol: Tdgf1
Name: teratocarcinoma-derived growth factor 1
Description: Predicted to have several functions, including Wnt-protein binding activity; nodal binding activity; and signaling receptor binding activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; cellular response to growth factor stimulus; and circulatory system development. Predicted to localize to several cellular components, including apical plasma membrane; membrane raft; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in colon cancer and congenital heart disease. Orthologous to human TDGF1 (teratocarcinoma-derived growth factor 1); PARTICIPATES IN glypican signaling pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl (ortholog); 2,2',5,5'-tetrachlorobiphenyl (ortholog); 5-fluorouracil (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC680246; similar to Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor)
Homo sapiens (human) : TDGF1 (teratocarcinoma-derived growth factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Tdgf1 (teratocarcinoma-derived growth factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tdgf1 (teratocarcinoma-derived growth factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TDGF1 (teratocarcinoma-derived growth factor 1)
Canis lupus familiaris (dog) : TDGF1 (teratocarcinoma-derived growth factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tdgf1 (teratocarcinoma-derived growth factor 1)
Sus scrofa (pig) : TDGF1 (teratocarcinoma-derived growth factor 1)
Chlorocebus sabaeus (African green monkey) : TDGF1 (teratocarcinoma-derived growth factor 1)
Heterocephalus glaber (naked mole-rat) : Tdgf1 (teratocarcinoma-derived growth factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.08119,215,266 - 119,220,909 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8119,215,495 - 119,219,232 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08118,554,829 - 118,560,094 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48115,341,587 - 115,346,871 (-)NCBIRGSC3.4rn4RGSC3.4
Celera8110,206,645 - 110,212,260 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Tdgf1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1594185
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.