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Gene: Tdgf1 (teratocarcinoma-derived growth factor 1) Rattus norvegicus
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Symbol: Tdgf1
Name: teratocarcinoma-derived growth factor 1
Description: Predicted to have several functions, including Wnt-protein binding activity; nodal binding activity; and signaling receptor binding activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; cellular response to growth factor stimulus; and circulatory system development. Predicted to localize to several cellular components, including apical plasma membrane; membrane raft; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in colon cancer and congenital heart disease. Orthologous to human TDGF1 (teratocarcinoma-derived growth factor 1); PARTICIPATES IN glypican signaling pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl (ortholog); 2,2',5,5'-tetrachlorobiphenyl (ortholog); 5-fluorouracil (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC680246; similar to Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor)
Orthologs:
Homo sapiens (human) : TDGF1 (teratocarcinoma-derived growth factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Tdgf1 (teratocarcinoma-derived growth factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tdgf1 (teratocarcinoma-derived growth factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TDGF1 (teratocarcinoma-derived growth factor 1)
Canis lupus familiaris (dog) : TDGF1 (teratocarcinoma-derived growth factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tdgf1 (teratocarcinoma-derived growth factor 1)
Sus scrofa (pig) : TDGF1 (teratocarcinoma-derived growth factor 1)
Chlorocebus sabaeus (African green monkey) : TDGF1 (teratocarcinoma-derived growth factor 1)
Heterocephalus glaber (naked mole-rat) : Tdgf1 (teratocarcinoma-derived growth factor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08119,215,266 - 119,220,909 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8119,215,495 - 119,219,232 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08118,554,829 - 118,560,094 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48115,341,587 - 115,346,871 (-)NCBIRGSC3.4rn4RGSC3.4
Celera8110,206,645 - 110,212,260 (-)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tdgf1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1594185
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.