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Gene: Cox10 (cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10) Rattus norvegicus
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Symbol: Cox10
Name: cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10
Description: Predicted to contribute to cytochrome-c oxidase activity. Predicted to be involved in several processes, including heme a biosynthetic process; mitochondrial fission; and respiratory chain complex IV assembly. Predicted to localize to the cytochrome complex; cytoplasm; and nucleolus. Human ortholog(s) of this gene implicated in Leigh disease and cytochrome-c oxidase deficiency disease. Orthologous to human COX10 (cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10); PARTICIPATES IN acute intermittent porphyria pathway; erythropoietic porphyria pathway; hereditary coproporphyria pathway; INTERACTS WITH (RS)-amphetamine; dioxygen; endosulfan.
Type: protein-coding
RefSeq Status: MODEL
Also known as: COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor; COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase; COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast); cytochrome c oxidase assembly homolog 10; cytochrome c oxidase assembly homolog 10 (yeast); LOC691853; protoheme IX farnesyltransferase, mitochondrial; similar to COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01050,439,778 - 50,563,920 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01050,207,540 - 50,331,232 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41050,191,370 - 50,230,838 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1047,863,873 - 47,975,130 (-)NCBICelera
Cytogenetic Map10q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Cox10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1594623
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.