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Gene: Alyref (Aly/REF export factor) Rattus norvegicus
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Symbol: Alyref
Name: Aly/REF export factor
Description: Predicted to have RNA binding activity and single-stranded DNA binding activity. Predicted to be involved in several processes, including mRNA export from nucleus; regulation of nucleobase-containing compound metabolic process; and viral mRNA export from host cell nucleus. Predicted to colocalize with the exon-exon junction complex and nuclear chromosome, telomeric region. Orthologous to human ALYREF (Aly/REF export factor); PARTICIPATES IN NXF1-NXT1 export pathway; mRNA decay pathway; RNA transport pathway; INTERACTS WITH (+)-schisandrin B; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC690585; similar to THO complex subunit 4 (Tho4) (RNA and export factor binding protein 1) (REF1-I) (Ally of AML-1 and LEF-1) (Aly/REF); THO complex 4; THO complex subunit 4; Thoc4
Orthologs:
Homo sapiens (human) : ALYREF (Aly/REF export factor)  HGNC  Alliance
Mus musculus (house mouse) : Alyref (Aly/REF export factor)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Alyref (Aly/REF export factor)
Pan paniscus (bonobo/pygmy chimpanzee) : ALYREF (Aly/REF export factor)
Canis lupus familiaris (dog) : ALYREF (Aly/REF export factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Alyref (Aly/REF export factor)
Sus scrofa (pig) : ALYREF (Aly/REF export factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.010109,768,593 - 109,774,639 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.010109,363,929 - 109,367,692 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410109,984,500 - 109,988,263 (-)NCBIRGSC3.4rn4RGSC3.4
Celera10104,414,714 - 104,418,477 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Alyref
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1594679
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.