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Gene: Smurf1 (SMAD specific E3 ubiquitin protein ligase 1) Rattus norvegicus
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Symbol: Smurf1
Name: SMAD specific E3 ubiquitin protein ligase 1
Description: Predicted to have I-SMAD binding activity; R-SMAD binding activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including autophagosome assembly; negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and ubiquitin-dependent protein catabolic process. Localizes to the axon and neuronal cell body. Predicted to colocalize with the mitochondrion. Orthologous to human SMURF1 (SMAD specific E3 ubiquitin protein ligase 1); PARTICIPATES IN Bone morphogenetic proteins signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: E3 ubiquitin-protein ligase SMURF1; LOC690516; RGD1309707; similar to Smad ubiquitination regulatory factor 1 isoform 2
Orthologs:
Homo sapiens (human) : SMURF1 (SMAD specific E3 ubiquitin protein ligase 1)  HGNC  Alliance
Mus musculus (house mouse) : Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SMURF1 (SMAD specific E3 ubiquitin protein ligase 1)
Canis lupus familiaris (dog) : SMURF1 (SMAD specific E3 ubiquitin protein ligase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smurf1 (SMAD specific E3 ubiquitin protein ligase 1)
Sus scrofa (pig) : SMURF1 (SMAD specific E3 ubiquitin protein ligase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01211,433,815 - 11,526,465 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1211,407,213 - 11,526,465 (+)Ensembl
Rnor_5.01213,499,018 - 13,591,105 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4129,950,304 - 10,042,391 (+)NCBIRGSC3.4rn4RGSC3.4
Celera1211,439,779 - 11,530,606 (+)NCBICelera
Cytogenetic Map12p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Smurf1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1594738
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.