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Gene: Mbd2 (methyl-CpG binding domain protein 2) Rattus norvegicus
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Symbol: Mbd2
Name: methyl-CpG binding domain protein 2
Description: Exhibits chromatin binding activity. Involved in several processes, including maternal behavior; regulation of nucleobase-containing compound metabolic process; and response to estradiol. Localizes to the nuclear chromatin. Used to study choline deficiency disease. Biomarker of choline deficiency disease; transient cerebral ischemia; and visual epilepsy. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human MBD2 (methyl-CpG binding domain protein 2); PARTICIPATES IN CHD family mediated chromatin remodeling pathway; DNA modification pathway; INTERACTS WITH 17beta-estradiol; bis(2-ethylhexyl) phthalate; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC291525; LOC680172; LOC684150; methyl-CpG-binding domain protein 2; MGC188552; similar to Methyl-CpG-binding domain protein 2 (Methyl-CpG-binding protein MBD2)
Orthologs:
Homo sapiens (human) : MBD2 (methyl-CpG binding domain protein 2)  HGNC  Alliance
Mus musculus (house mouse) : Mbd2 (methyl-CpG binding domain protein 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mbd2 (methyl-CpG binding domain protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MBD2 (methyl-CpG binding domain protein 2)
Canis lupus familiaris (dog) : MBD2 (methyl-CpG binding domain protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mbd2 (methyl-CpG binding domain protein 2)
Sus scrofa (pig) : MBD2 (methyl-CpG binding domain protein 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01865,814,026 - 65,885,115 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01864,990,480 - 65,060,941 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41867,281,440 - 67,348,558 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11867,378,120 - 67,421,847 (+)NCBI
Celera1862,237,373 - 62,304,615 (+)NCBICelera
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mbd2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1595452
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.