Gene: RT1-Ba (RT1 class II, locus Ba) Rattus norvegicus
Symbol: RT1-Ba
Name: RT1 class II, locus Ba
Description: Exhibits protein heterodimerization activity; involved in cellular response to glucocorticoid stimulus and negative regulation of T cell proliferation; predicted to localize to the MHC class II protein complex, external side of plasma membrane, and lysosome; used to study uveitis; orthologous to several human genes including HLA-DQA1 (major histocompatibility complex, class II, DQ alpha 1); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; asthma pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: activated B cell RT1Bl alpha chain; BA1; MGC105667; MHC class I antigen; MHC class II antigen RT1.B alpha chain; Rano class II histocompatibility antigen, B alpha chain; RT1 class II antigen, Ba chain; RT1 class II, locus Ba (mapped); RT1-B alpha; RT1-Ba_mapped
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0204,066,133 - 4,070,726 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0206,146,271 - 6,150,864 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,697,971 - 4,702,564 (+)NCBIRGSC3.4rn4RGSC3.4
Celera206,176,966 - 6,181,559 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on RT1-Ba
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1595867
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-05-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.