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Gene: RT1-CE5 (RT1 class I, locus CE5) Rattus norvegicus
Symbol: RT1-CE5
Name: RT1 class I, locus CE5
Description: Predicted to have several functions, including 14-3-3 protein binding activity; TAP binding activity; and beta-2-microglobulin binding activity. Predicted to be involved in several processes, including antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; antigen processing and presentation of endogenous peptide antigen via MHC class Ib; and regulation of lymphocyte mediated immunity. Predicted to localize to several cellular components, including MHC class Ib protein complex; bounding membrane of organelle; and external side of plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; asthma (multiple); bone inflammation disease (multiple); eye disease (multiple); and inner ear disease (multiple). Orthologous to several human genes including HLA-F (major histocompatibility complex, class I, F); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; autoimmune thyroiditis pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC112896; MHC class I protein; MHC class Ib antigen; RT1 class I, CE5; RT1-C/E5; rt1-E2; rt1-El
Homo sapiens (human) : HLA-F (major histocompatibility complex, class I, F)  HGNC  Alliance
Mus musculus (house mouse) : Gm11127 (predicted gene 11127)  MGI  Alliance
Canis lupus familiaris (dog) : DLA-79 (MHC class Ib)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0204,892,702 - 4,896,993 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl204,892,702 - 4,896,991 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0206,968,846 - 6,973,135 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,509,593 - 3,513,732NCBIRGSC3.4rn4RGSC3.4
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on RT1-CE5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1595868
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.