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Gene: Smg6 (SMG6 nonsense mediated mRNA decay factor) Rattus norvegicus
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Symbol: Smg6
Name: SMG6 nonsense mediated mRNA decay factor
Description: Predicted to have several functions, including DNA polymerase binding activity; endoribonuclease activity; and nucleic acid binding activity. Predicted to be involved in nucleic acid metabolic process and regulation of telomere maintenance. Predicted to colocalize with exon-exon junction complex. Orthologous to human SMG6 (SMG6 nonsense mediated mRNA decay factor); PARTICIPATES IN mRNA decay pathway; INTERACTS WITH 17alpha-ethynylestradiol; acrylamide; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC287522; LOC303309; LRRGT00040; RGD1309609; similar to KIAA0732 protein; similar to Telomerase-binding protein EST1A (Ever shorter telomeres 1A) (Telomerase subunit EST1A) (EST1-like protein A); Smg-6 homolog, nonsense mediated mRNA decay factor; Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans); telomerase-binding protein EST1A
Orthologs:
Homo sapiens (human) : SMG6 (SMG6 nonsense mediated mRNA decay factor)  HGNC  Alliance
Mus musculus (house mouse) : Smg6 (Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smg6 (SMG6 nonsense mediated mRNA decay factor)
Pan paniscus (bonobo/pygmy chimpanzee) : SMG6 (SMG6 nonsense mediated mRNA decay factor)
Canis lupus familiaris (dog) : SMG6 (SMG6 nonsense mediated mRNA decay factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smg6 (SMG6 nonsense mediated mRNA decay factor)
Sus scrofa (pig) : SMG6 (SMG6 nonsense mediated mRNA decay factor)
Chlorocebus sabaeus (African green monkey) : SMG6 (SMG6 nonsense mediated mRNA decay factor)
Heterocephalus glaber (naked mole-rat) : Smg6 (SMG6 nonsense mediated mRNA decay factor)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01061,771,912 - 62,007,030 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.01061,526,024 - 61,542,583 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1061,772,449 - 62,007,030 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1061,527,462 - 61,540,774 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01061,248,898 - 61,263,673 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01061,493,274 - 61,721,420 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41062,234,450 - 62,470,611 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11062,437,519 - 62,461,510 (+)NCBI
Celera1058,816,443 - 59,044,342 (+)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Smg6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1595918
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.