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Gene: Iqsec1 (IQ motif and Sec7 domain ArfGEF 1) Rattus norvegicus
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Symbol: Iqsec1
Name: IQ motif and Sec7 domain ArfGEF 1
Description: Predicted to have protein kinase binding activity. Predicted to be involved in several processes, including positive regulation of adherens junction organization; positive regulation of keratinocyte migration; and regulation of postsynaptic neurotransmitter receptor internalization. Predicted to localize to several cellular components, including the Schaffer collateral - CA1 synapse; nucleolus; and postsynaptic density, intracellular component. Orthologous to human IQSEC1 (IQ motif and Sec7 domain 1); INTERACTS WITH bisphenol A; flutamide; 2-methylcholine (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: IQ motif and Sec7 domain 1; IQ motif and SEC7 domain-containing protein 1; LOC686590; LOW QUALITY PROTEIN: IQ motif and SEC7 domain-containing protein 1; similar to IQ motif and Sec7 domain 1
Orthologs:
Homo sapiens (human) : IQSEC1 (IQ motif and Sec7 domain ArfGEF 1)  HGNC  Alliance
Mus musculus (house mouse) : Iqsec1 (IQ motif and Sec7 domain 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Iqsec1 (IQ motif and Sec7 domain ArfGEF 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IQSEC1 (IQ motif and Sec7 domain ArfGEF 1)
Canis lupus familiaris (dog) : IQSEC1 (IQ motif and Sec7 domain 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Iqsec1 (IQ motif and Sec7 domain ArfGEF 1)
Sus scrofa (pig) : IQSEC1 (IQ motif and Sec7 domain ArfGEF 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04123,400,717 - 123,454,656 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04187,091,489 - 187,212,029 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera4112,091,878 - 112,411,666 (-)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Iqsec1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1596313
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-09-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.