Gene: Iqsec2 (IQ motif and Sec7 domain 2) Rattus norvegicus
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Symbol: Iqsec2
Name: IQ motif and Sec7 domain 2
Description: Predicted to have ARF guanyl-nucleotide exchange factor activity; involved in positive regulation of glutamatergic synaptic transmission and positive regulation of long-term synaptic depression; predicted to localize to several cellular components, including the Schaffer collateral - CA1 synapse, glutamatergic synapse, and postsynaptic density; orthologous to human IQSEC2 (IQ motif and Sec7 domain 2); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; glycidol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: IQ motif and SEC7 domain-containing protein 2; LOC685244; RGD1562109; similar to IQ motif and Sec7 domain 2
Orthologs:
Homo sapiens (human) : IQSEC2 (IQ motif and Sec7 domain 2)  HGNC  Alliance
Mus musculus (house mouse) : Iqsec2 (IQ motif and Sec7 domain 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Iqsec2 (IQ motif and Sec7 domain 2)
Pan paniscus (bonobo/pygmy chimpanzee) : IQSEC2 (IQ motif and Sec7 domain 2)
Canis lupus familiaris (dog) : IQSEC2 (IQ motif and Sec7 domain 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Iqsec2 (IQ motif and Sec7 domain 2)
Sus scrofa (pig) : IQSEC2 (IQ motif and Sec7 domain 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X22,212,137 - 22,293,810 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X64,286,343 - 64,367,399 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X41,651,275 - 41,733,435 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX21,517,185 - 21,598,702 (+)NCBICelera
Cytogenetic MapXq13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Iqsec2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1596452
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.