Gene: Iqsec2 (IQ motif and Sec7 domain 2) Rattus norvegicus
Symbol: Iqsec2
Name: IQ motif and Sec7 domain 2
Description: Predicted to have ARF guanyl-nucleotide exchange factor activity; involved in positive regulation of glutamatergic synaptic transmission and positive regulation of long-term synaptic depression; predicted to localize to several cellular components, including the Schaffer collateral - CA1 synapse, glutamatergic synapse, and postsynaptic density; orthologous to human IQSEC2 (IQ motif and Sec7 domain 2); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; glycidol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: IQ motif and SEC7 domain-containing protein 2; LOC685244; RGD1562109; similar to IQ motif and Sec7 domain 2
Homo sapiens (human) : IQSEC2 (IQ motif and Sec7 domain 2)  HGNC  Alliance
Mus musculus (house mouse) : Iqsec2 (IQ motif and Sec7 domain 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Iqsec2 (IQ motif and Sec7 domain 2)
Pan paniscus (bonobo/pygmy chimpanzee) : IQSEC2 (IQ motif and Sec7 domain 2)
Canis lupus familiaris (dog) : IQSEC2 (IQ motif and Sec7 domain 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Iqsec2 (IQ motif and Sec7 domain 2)
Sus scrofa (pig) : IQSEC2 (IQ motif and Sec7 domain 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X22,212,137 - 22,293,810 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X64,286,343 - 64,367,399 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X41,651,275 - 41,733,435 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX21,517,185 - 21,598,702 (+)NCBICelera
Cytogenetic MapXq13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Iqsec2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1596452
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.