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Gene: Msrb3 (methionine sulfoxide reductase B3) Rattus norvegicus
Symbol: Msrb3
Name: methionine sulfoxide reductase B3
Description: Predicted to have peptide-methionine (R)-S-oxide reductase activity and zinc ion binding activity. Predicted to be involved in protein repair. Predicted to localize to the endoplasmic reticulum and mitochondrion. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 74. Orthologous to human MSRB3 (methionine sulfoxide reductase B3); PARTICIPATES IN glycine N-methyltransferase deficiency pathway; homocystinuria pathway; hypermethioninemia pathway; INTERACTS WITH dioxygen; endosulfan; glyphosate.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC680036; methionine-R-sulfoxide reductase B3; similar to methionine sulfoxide reductase B3 isoform 2
Homo sapiens (human) : MSRB3 (methionine sulfoxide reductase B3)  HGNC  Alliance
Mus musculus (house mouse) : Msrb3 (methionine sulfoxide reductase B3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Msrb3 (methionine sulfoxide reductase B3)
Pan paniscus (bonobo/pygmy chimpanzee) : MSRB3 (methionine sulfoxide reductase B3)
Canis lupus familiaris (dog) : MSRB3 (methionine sulfoxide reductase B3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Msrb3 (methionine sulfoxide reductase B3)
Sus scrofa (pig) : MSRB3 (methionine sulfoxide reductase B3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0762,850,506 - 62,972,487 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl762,850,515 - 62,972,084 (-)Ensembl
Rnor_5.0762,835,857 - 62,954,890 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4760,148,413 - 60,206,141 (-)NCBIRGSC3.4rn4RGSC3.4
Celera753,051,311 - 53,172,931 (-)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Msrb3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1596851
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.