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Gene: Prame (preferentially expressed antigen in melanoma) Rattus norvegicus
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Symbol: Prame
Name: preferentially expressed antigen in melanoma
Description: Predicted to have retinoic acid receptor binding activity. Predicted to be involved in several processes, including negative regulation of apoptotic process; negative regulation of retinoic acid receptor signaling pathway; and negative regulation of transcription, DNA-templated. Predicted to localize to cytoplasm; nucleoplasm; and plasma membrane. Human ortholog(s) of this gene implicated in myeloid leukemia. Orthologous to human PRAME (preferentially expressed antigen in melanoma); INTERACTS WITH bisphenol A; 1,2-dichloroethane (ortholog); 17beta-estradiol (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC308656; LOC680000; melanoma antigen preferentially expressed in tumors; rCG38045-like; similar to preferentially expressed antigen in melanoma-like 3
Orthologs:
Homo sapiens (human) : PRAME (preferentially expressed antigen in melanoma)  HGNC  Alliance
Mus musculus (house mouse) : Prame (preferentially expressed antigen in melanoma)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prame (preferentially expressed antigen in melanoma)
Canis lupus familiaris (dog) : PRAME (preferentially expressed antigen in melanoma)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prame (preferentially expressed antigen in melanoma)
Sus scrofa (pig) : PRAME (preferentially expressed antigen in melanoma)
Heterocephalus glaber (naked mole-rat) : Prame (preferentially expressed antigen in melanoma)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X106,082,984 - 106,091,256 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX106,083,203 - 106,085,878 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X105,969,013 - 105,977,129 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X122,878,213 - 122,880,888 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX99,586,294 - 99,594,559 (-)NCBICelera
Cytogenetic MapXq32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Prame
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1596887
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.