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Gene: Prame (preferentially expressed antigen in melanoma) Rattus norvegicus
Symbol: Prame
Name: preferentially expressed antigen in melanoma
Description: Predicted to have retinoic acid receptor binding activity. Predicted to be involved in several processes, including negative regulation of apoptotic process; negative regulation of retinoic acid receptor signaling pathway; and negative regulation of transcription, DNA-templated. Predicted to localize to cytoplasm; nucleoplasm; and plasma membrane. Human ortholog(s) of this gene implicated in myeloid leukemia. Orthologous to human PRAME (preferentially expressed antigen in melanoma); INTERACTS WITH bisphenol A; 1,2-dichloroethane (ortholog); 17beta-estradiol (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC308656; LOC680000; melanoma antigen preferentially expressed in tumors; rCG38045-like; similar to preferentially expressed antigen in melanoma-like 3
Homo sapiens (human) : PRAME (preferentially expressed antigen in melanoma)  HGNC  Alliance
Mus musculus (house mouse) : Prame (preferentially expressed antigen in melanoma)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prame (preferentially expressed antigen in melanoma)
Canis lupus familiaris (dog) : PRAME (preferentially expressed antigen in melanoma)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prame (preferentially expressed antigen in melanoma)
Sus scrofa (pig) : PRAME (preferentially expressed antigen in melanoma)
Heterocephalus glaber (naked mole-rat) : Prame (preferentially expressed antigen in melanoma)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X106,082,984 - 106,091,256 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX106,083,203 - 106,085,878 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X105,969,013 - 105,977,129 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X122,878,213 - 122,880,888 (+)NCBIRGSC3.4rn4RGSC3.4
CeleraX99,586,294 - 99,594,559 (-)NCBICelera
Cytogenetic MapXq32NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Prame
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1596887
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.