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Gene: Glb1 (galactosidase, beta 1) Rattus norvegicus
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Symbol: Glb1
Name: galactosidase, beta 1
Description: Exhibits beta-galactosidase activity and galactoside binding activity. Involved in galactose catabolic process; response to Thyroglobulin triiodothyronine; and response to cortisone. Localizes to the lysosome. Human ortholog(s) of this gene implicated in GM1 gangliosidosis; GM1 gangliosidosis type 1; GM1 gangliosidosis type 2; GM1 gangliosidosis type 3; and mucopolysaccharidosis IV. Orthologous to human GLB1 (galactosidase beta 1); PARTICIPATES IN Fabry disease pathway; galactose metabolic pathway; galactosemia pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; aldehydo-D-glucose.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: beta-galactosidase; galactosidase, beta 1 (mapped); Glb1_mapped
Orthologs:
Homo sapiens (human) : GLB1 (galactosidase beta 1)  HGNC  Alliance
Mus musculus (house mouse) : Glb1 (galactosidase, beta 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Glb1 (galactosidase beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GLB1 (galactosidase beta 1)
Canis lupus familiaris (dog) : GLB1 (galactosidase beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Glb1 (galactosidase beta 1)
Sus scrofa (pig) : GLB1 (galactosidase beta 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08122,439,328 - 122,511,939 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8122,439,328 - 122,511,939 (+)Ensembl
Rnor_5.08121,752,146 - 121,824,793 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48118,791,550 - 118,864,281 (+)NCBIRGSC3.4rn4RGSC3.4
Celera8113,332,049 - 113,404,466 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Glb1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1597145
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.