Gene: Brk1 (BRICK1 subunit of SCAR/WAVE actin nucleating complex) Rattus norvegicus
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Symbol: Brk1
Name: BRICK1 subunit of SCAR/WAVE actin nucleating complex
Description: Predicted to contribute to Rac GTPase binding activity; predicted to be involved in several processes, including Rac protein signal transduction, actin cytoskeleton organization, and positive regulation of cellular component organization; predicted to localize to the SCAR complex and lamellipodium; orthologous to human BRK1 (BRICK1, SCAR/WAVE actin nucleating complex subunit); PARTICIPATES IN platelet-derived growth factor signaling pathway; INTERACTS WITH bisphenol A; Brodifacoum; flutamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BRICK1, SCAR/WAVE actin-nucleating complex subunit; hypothetical protein LOC679934; LOC679934; probable protein BRICK1; similar to chromosome 3 open reading frame 10
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04145,559,206 - 145,574,438 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04208,855,604 - 208,870,836 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44149,507,741 - 149,522,713 (+)NCBIRGSC3.4rn4RGSC3.4
Celera4135,305,443 - 135,320,375 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Brk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1598136
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.