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Gene: Plekha7 (pleckstrin homology domain containing A7) Rattus norvegicus
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Symbol: Plekha7
Name: pleckstrin homology domain containing A7
CRRD ID: 1598216
Description: Predicted to have delta-catenin binding activity. Predicted to be involved in several processes, including cell-cell adhesion mediated by cadherin; pore complex assembly; and zonula adherens maintenance. Predicted to localize to several cellular components, including centrosome; pore complex; and zonula adherens. Used to study glomerulosclerosis and hypertension. Orthologous to human PLEKHA7 (pleckstrin homology domain containing A7); PARTICIPATES IN E-cadherin signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; endosulfan.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC499249; pleckstrin homology domain containing, family A member 7; pleckstrin homology domain-containing family A member 7; RGD1304650; similar to Plekha7 protein
Orthologs:
Homo sapiens (human) : PLEKHA7 (pleckstrin homology domain containing A7)  HGNC  Alliance
Mus musculus (house mouse) : Plekha7 (pleckstrin homology domain containing, family A member 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plekha7 (pleckstrin homology domain containing A7)
Pan paniscus (bonobo/pygmy chimpanzee) : PLEKHA7 (pleckstrin homology domain containing A7)
Canis lupus familiaris (dog) : PLEKHA7 (pleckstrin homology domain containing A7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plekha7 (pleckstrin homology domain containing A7)
Sus scrofa (pig) : PLEKHA7 (pleckstrin homology domain containing A7)
Chlorocebus sabaeus (African green monkey) : PLEKHA7 (pleckstrin homology domain containing A7)
Heterocephalus glaber (naked mole-rat) : Plekha7 (pleckstrin homology domain containing A7)
more info ...
Allele / Splice: Plekha7em1Mcwi   Plekha7em4Mcwi  
Genetic Models: SS-Plekha7em4Mcwi SS-Plekha7em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01185,427,600 - 185,493,985 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1185,356,975 - 185,538,694 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01192,397,589 - 192,463,974 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41174,249,022 - 174,316,226 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1168,231,482 - 168,298,068 (-)NCBICelera
Cytogenetic Map1q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Plekha7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1598216
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.