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Gene: Plekha7 (pleckstrin homology domain containing A7) Rattus norvegicus
Symbol: Plekha7
Name: pleckstrin homology domain containing A7
CRRD ID: 1598216
Description: Predicted to have delta-catenin binding activity. Predicted to be involved in several processes, including cell-cell adhesion mediated by cadherin; pore complex assembly; and zonula adherens maintenance. Predicted to localize to several cellular components, including centrosome; pore complex; and zonula adherens. Used to study glomerulosclerosis and hypertension. Orthologous to human PLEKHA7 (pleckstrin homology domain containing A7); PARTICIPATES IN E-cadherin signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; endosulfan.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC499249; pleckstrin homology domain containing, family A member 7; pleckstrin homology domain-containing family A member 7; RGD1304650; similar to Plekha7 protein
Homo sapiens (human) : PLEKHA7 (pleckstrin homology domain containing A7)  HGNC  Alliance
Mus musculus (house mouse) : Plekha7 (pleckstrin homology domain containing, family A member 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plekha7 (pleckstrin homology domain containing A7)
Pan paniscus (bonobo/pygmy chimpanzee) : PLEKHA7 (pleckstrin homology domain containing A7)
Canis lupus familiaris (dog) : PLEKHA7 (pleckstrin homology domain containing A7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plekha7 (pleckstrin homology domain containing A7)
Sus scrofa (pig) : PLEKHA7 (pleckstrin homology domain containing A7)
Chlorocebus sabaeus (African green monkey) : PLEKHA7 (pleckstrin homology domain containing A7)
Heterocephalus glaber (naked mole-rat) : Plekha7 (pleckstrin homology domain containing A7)
more info ...
Allele / Splice: Plekha7em1Mcwi   Plekha7em4Mcwi  
Genetic Models: SS-Plekha7em4Mcwi SS-Plekha7em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01185,427,600 - 185,493,985 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1185,356,975 - 185,538,694 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01192,397,589 - 192,463,974 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41174,249,022 - 174,316,226 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1168,231,482 - 168,298,068 (-)NCBICelera
Cytogenetic Map1q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Plekha7
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1598216
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.