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Gene: RT1-CE3 (RT1 class I, locus CE3) Rattus norvegicus
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Symbol: RT1-CE3
Name: RT1 class I, locus CE3
Description: Predicted to have peptide antigen binding activity and signaling receptor binding activity. Predicted to be involved in several processes, including antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; antigen processing and presentation of endogenous peptide antigen via MHC class Ib; and positive regulation of T cell mediated cytotoxicity. Predicted to localize to the external side of plasma membrane and extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Behcet's disease; asthma (multiple); bone inflammation disease (multiple); eye disease (multiple); and inner ear disease (multiple). Orthologous to several human genes including HLA-A (major histocompatibility complex, class I, A); HLA-B (major histocompatibility complex, class I, B); and HLA-E (major histocompatibility complex, class I, E); PARTICIPATES IN allograft rejection pathway; antigen processing and presentation pathway; autoimmune thyroiditis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',5,5'-tetrachlorobiphenyl; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MHC class I protein; MHC class I protein-like; RT1 class I, CE3; RT1-C/E3
Orthologs:
No known orthologs. homologs ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0204,918,047 - 4,943,603 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0207,008,109 - 7,011,516 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,552,207 - 3,555,613 (-)NCBIRGSC3.4rn4RGSC3.4
Celera205,715,502 - 5,766,602 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on RT1-CE3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1598231
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.