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Gene: Mov10 (Mov10 RISC complex RNA helicase) Rattus norvegicus
Symbol: Mov10
Name: Mov10 RISC complex RNA helicase
Description: Predicted to have 5'-3' RNA helicase activity and RNA binding activity. Predicted to be involved in several processes, including negative regulation of transposition, RNA-mediated; posttranscriptional regulation of gene expression; and regulation of neuron projection arborization. Predicted to localize to several cellular components, including cytoplasmic ribonucleoprotein granule; cytosol; and viral replication complex. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human MOV10 (Mov10 RISC complex RNA helicase); INTERACTS WITH (+)-schisandrin B; 4,4'-diaminodiphenylmethane; 6-propyl-2-thiouracil.
Type: protein-coding
Also known as: capping protein (actin filament) muscle Z-line, alpha 1; Capza1; LOC310756; Moloney leukemia virus 10; Mov10, Moloney leukemia virus 10; putative helicase MOV-10; similar to Moloney leukemia virus 10
Homo sapiens (human) : MOV10 (Mov10 RISC complex RNA helicase)  HGNC  Alliance
Mus musculus (house mouse) : Mov10 (Mov10 RISC complex RNA helicase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mov10 (Mov10 RISC complex RNA helicase)
Pan paniscus (bonobo/pygmy chimpanzee) : MOV10 (Mov10 RISC complex RNA helicase)
Canis lupus familiaris (dog) : MOV10 (Mov10 RISC complex RNA helicase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mov10 (Mov10 RISC complex RNA helicase)
Sus scrofa (pig) : MOV10 (Mov10 RISC complex RNA helicase)
Chlorocebus sabaeus (African green monkey) : MOV10 (Mov10 RISC complex RNA helicase)
Heterocephalus glaber (naked mole-rat) : Mov10 (Mov10 RISC complex RNA helicase)
more info ...
Allele / Splice: Mov10Tn(sb-T2/Bart3)2.281Mcwi  
Genetic Models: F344-Mov10Tn(sb-T2/Bart3)2.281Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02207,277,088 - 207,301,245 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2207,278,161 - 207,300,854 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02226,696,252 - 226,717,551 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42200,053,185 - 200,075,536 (-)NCBIRGSC3.4rn4RGSC3.4
Celera2184,758,910 - 184,780,976 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Mov10
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1598327
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.