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Gene: THOC6 (THO complex 6) Homo sapiens
Symbol: THOC6
Name: THO complex 6
Description: Predicted to have RNA binding activity. Involved in several processes, including mRNA export from nucleus; negative regulation of apoptotic process; and viral mRNA export from host cell nucleus. Localizes to the THO complex part of transcription export complex and nuclear speck. Colocalizes with the nuclear chromosome, telomeric region.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BBIS; fSAP35; functional spliceosome-associated protein 35; MGC2655; THO complex 6 homolog; THO complex subunit 6 homolog; WD repeat domain 58; WD repeat-containing protein 58; WDR58
Mus musculus (house mouse) : Thoc6 (THO complex 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Thoc6 (THO complex 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Thoc6 (THO complex 6)
Pan paniscus (bonobo/pygmy chimpanzee) : THOC6 (THO complex 6)
Canis lupus familiaris (dog) : THOC6 (THO complex 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Thoc6 (THO complex 6)
Sus scrofa (pig) : THOC6 (THO complex 6)
Chlorocebus sabaeus (African green monkey) : THOC6 (THO complex 6)
Heterocephalus glaber (naked mole-rat) : Thoc6 (THO complex 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl163,024,027 - 3,027,755 (+)Ensembl
GRCh38163,024,035 - 3,027,750 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37163,074,032 - 3,077,756 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36163,014,094 - 3,017,752 (+)NCBINCBI36hg18NCBI36
Celera163,279,588 - 3,283,311 (+)NCBI
Cytogenetic Map16p13.3NCBI
HuRef163,045,606 - 3,049,329 (+)NCBIHuRef
CHM1_1163,073,906 - 3,077,630 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on THOC6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1601739
Created: 2007-04-27
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.