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Gene: AFF4 (AF4/FMR2 family member 4) Homo sapiens
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Symbol: AFF4
Name: AF4/FMR2 family member 4
Description: Predicted to have DNA-binding transcription factor activity and double-stranded DNA binding activity. Predicted to be involved in transcription elongation from RNA polymerase II promoter. Localizes to the fibrillar center and transcription elongation factor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AF4/FMR2 family, member 4; AF5Q31; ALL1 fused gene from 5q31; ALL1-fused gene from chromosome 5q31 protein; CHOPS; major CDK9 elongation factor-associated protein; MCEF; MGC75036
Orthologs:
Mus musculus (house mouse) : Aff4 (AF4/FMR2 family, member 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Aff4 (AF4/FMR2 family, member 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aff4 (AF4/FMR2 family member 4)
Pan paniscus (bonobo/pygmy chimpanzee) : AFF4 (AF4/FMR2 family member 4)
Canis lupus familiaris (dog) : AFF4 (AF4/FMR2 family member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aff4 (AF4/FMR2 family member 4)
Sus scrofa (pig) : AFF4 (AF4/FMR2 family member 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385132,875,381 - 132,963,655 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375132,211,071 - 132,299,354 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365132,238,970 - 132,327,253 (-)NCBINCBI36hg18NCBI36
Celera5128,341,097 - 128,429,374 (-)NCBI
Cytogenetic Map5q31.1NCBI
HuRef5127,403,706 - 127,491,391 (-)NCBIHuRef
CHM1_15131,644,358 - 131,732,653 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on AFF4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1601873
Created: 2007-04-27
Species: Homo sapiens
Last Modified: 2019-10-29
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.