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Gene: KALRN (kalirin RhoGEF kinase) Homo sapiens
Symbol: KALRN
Name: kalirin RhoGEF kinase
Description: Exhibits guanyl-nucleotide exchange factor activity. Predicted to be involved in intracellular signal transduction and nervous system development. Localizes to the cytosol and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ARHGEF24; CHD5; CHDS5; DUET; DUO; FLJ12332; FLJ16443; FLJ18196; FLJ18623; HAPIP; huntingtin-associated protein interacting protein (duo); kalirin; kalirin, RhoGEF kinase; RP11-71H17.7; serine/threonine kinase with Dbl- and pleckstrin homology domains; serine/threonine-protein kinase with Dbl- and pleckstrin homology domain; TRAD
Mus musculus (house mouse) : Kalrn (kalirin, RhoGEF kinase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Kalrn (kalirin, RhoGEF kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kalrn (kalirin RhoGEF kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : KALRN (kalirin RhoGEF kinase)
Canis lupus familiaris (dog) : KALRN (kalirin RhoGEF kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kalrn (kalirin RhoGEF kinase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl3124,080,023 - 124,726,325 (+)Ensembl
GRCh383124,033,341 - 124,726,325 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373123,813,558 - 124,440,036 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363125,296,275 - 125,922,726 (+)NCBINCBI36hg18NCBI36
Celera3122,221,230 - 122,847,210 (+)NCBI
Cytogenetic Map3q21.1-q21.2NCBI
HuRef3121,187,838 - 121,814,322 (+)NCBIHuRef
CHM1_13123,776,528 - 124,408,158 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KALRN
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1601887
Created: 2007-04-27
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.