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Gene: TMEM127 (transmembrane protein 127) Homo sapiens
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Symbol: TMEM127
Name: transmembrane protein 127
Description: Exhibits Rab GTPase binding activity. Involved in negative regulation of TOR signaling and negative regulation of cell population proliferation. Localizes to the early endosome and plasma membrane. Implicated in pheochromocytoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ20507; FLJ22257
Orthologs:
Mus musculus (house mouse) : Tmem127 (transmembrane protein 127)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tmem127 (transmembrane protein 127)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmem127 (transmembrane protein 127)
Pan paniscus (bonobo/pygmy chimpanzee) : TMEM127 (transmembrane protein 127)
Canis lupus familiaris (dog) : TMEM127 (transmembrane protein 127)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmem127 (transmembrane protein 127)
Sus scrofa (pig) : TMEM127 (transmembrane protein 127)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl296,248,516 - 96,265,994 (-)Ensembl
GRCh38296,248,514 - 96,265,997 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37296,915,946 - 96,931,751 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36296,280,039 - 96,295,459 (-)NCBINCBI36hg18NCBI36
Celera291,357,500 - 91,372,939 (-)NCBI
Cytogenetic Map2q11.2NCBI
HuRef290,877,443 - 90,893,248 (-)NCBIHuRef
CHM1_1296,920,300 - 96,936,106 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
 
More on TMEM127
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1601991
Created: 2007-04-27
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.