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Gene: NRROS (negative regulator of reactive oxygen species) Homo sapiens
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Symbol: NRROS
Name: negative regulator of reactive oxygen species
Description: Exhibits transforming growth factor beta binding activity. Predicted to be involved in several processes, including microglia development; sequestering of TGFbeta in extracellular matrix; and transforming growth factor beta1 activation. Localizes to the cell surface; INTERACTS WITH aflatoxin B1; cisplatin; dioxygen.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ELLP3030; GARPL1; leucine rich repeat containing 33; leucine-rich repeat-containing protein 33; LRRC33; MGC50789; transforming growth factor beta activator LRRC33; UNQ3030
Orthologs:
Mus musculus (house mouse) : Nrros (negative regulator of reactive oxygen species)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nrros (negative regulator of reactive oxygen species)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nrros (negative regulator of reactive oxygen species)
Pan paniscus (bonobo/pygmy chimpanzee) : NRROS (negative regulator of reactive oxygen species)
Canis lupus familiaris (dog) : NRROS (negative regulator of reactive oxygen species)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nrros (negative regulator of reactive oxygen species)
Sus scrofa (pig) : NRROS (negative regulator of reactive oxygen species)
Chlorocebus sabaeus (green monkey) : NRROS (negative regulator of reactive oxygen species)
Heterocephalus glaber (naked mole-rat) : Nrros (negative regulator of reactive oxygen species)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl3196,639,694 - 196,662,004 (+)Ensembl
GRCh383196,639,694 - 196,662,004 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373196,366,656 - 196,388,875 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363197,851,053 - 197,873,272 (+)NCBINCBI36hg18NCBI36
Celera3194,948,253 - 194,970,470 (+)NCBI
Cytogenetic Map3q29NCBI
HuRef3193,663,748 - 193,685,954 (+)NCBIHuRef
CHM1_13196,337,847 - 196,360,147 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NRROS
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1602040
Created: 2007-04-27
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.