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Gene: PARP2 (poly(ADP-ribose) polymerase 2) Homo sapiens
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Symbol: PARP2
Name: poly(ADP-ribose) polymerase 2
Description: Exhibits NAD DNA ADP-ribosyltransferase activity and protein ADP-ribosylase activity. Involved in DNA ADP-ribosylation; peptidyl-serine ADP-ribosylation; and protein poly-ADP-ribosylation. Localizes to the nucleolus and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADP-ribosyltransferase (NAD+, poly(ADP-ribose) polymerase)-like 2; ADP-ribosyltransferase diphtheria toxin-like 2; ADPRT-2; ADPRT2; ADPRTL2; ADPRTL3; ARTD2; DNA ADP-ribosyltransferase PARP2; hPARP-2; NAD(+) ADP-ribosyltransferase 2; pADPRT-2; PARP-2; poly (ADP-ribose) polymerase 2; poly (ADP-ribose) polymerase family, member 2; poly (ADP-ribosyl) transferase-like 2; poly [ADP-ribose] polymerase 2; poly(ADP-ribose) synthetase; poly[ADP-ribose] synthase 2; poly[ADP-ribose] synthetase 2
Orthologs:
Mus musculus (house mouse) : Parp2 (poly (ADP-ribose) polymerase family, member 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Parp2 (poly (ADP-ribose) polymerase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Parp2 (poly(ADP-ribose) polymerase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PARP2 (poly(ADP-ribose) polymerase 2)
Canis lupus familiaris (dog) : PARP2 (poly(ADP-ribose) polymerase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Parp2 (poly(ADP-ribose) polymerase 2)
Sus scrofa (pig) : PARP2 (poly(ADP-ribose) polymerase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381420,343,041 - 20,357,904 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371420,811,773 - 20,826,063 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361419,881,613 - 19,895,903 (+)NCBINCBI36hg18NCBI36
Celera14672,919 - 687,220 (+)NCBI
Cytogenetic Map14q11.2NCBI
HuRef14933,616 - 947,915 (+)NCBIHuRef
CHM1_11420,813,199 - 20,827,472 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PARP2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1602134
Created: 2007-04-27
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.