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Gene: PARP2 (poly(ADP-ribose) polymerase 2) Homo sapiens
Symbol: PARP2
Name: poly(ADP-ribose) polymerase 2
Description: Exhibits NAD DNA ADP-ribosyltransferase activity and protein ADP-ribosylase activity. Involved in DNA ADP-ribosylation; peptidyl-serine ADP-ribosylation; and protein poly-ADP-ribosylation. Localizes to the nucleolus and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADP-ribosyltransferase (NAD+, poly(ADP-ribose) polymerase)-like 2; ADP-ribosyltransferase diphtheria toxin-like 2; ADPRT-2; ADPRT2; ADPRTL2; ADPRTL3; ARTD2; DNA ADP-ribosyltransferase PARP2; hPARP-2; NAD(+) ADP-ribosyltransferase 2; pADPRT-2; PARP-2; poly (ADP-ribose) polymerase 2; poly (ADP-ribose) polymerase family, member 2; poly (ADP-ribosyl) transferase-like 2; poly [ADP-ribose] polymerase 2; poly(ADP-ribose) synthetase; poly[ADP-ribose] synthase 2; poly[ADP-ribose] synthetase 2
Mus musculus (house mouse) : Parp2 (poly (ADP-ribose) polymerase family, member 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Parp2 (poly (ADP-ribose) polymerase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Parp2 (poly(ADP-ribose) polymerase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PARP2 (poly(ADP-ribose) polymerase 2)
Canis lupus familiaris (dog) : PARP2 (poly(ADP-ribose) polymerase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Parp2 (poly(ADP-ribose) polymerase 2)
Sus scrofa (pig) : PARP2 (poly(ADP-ribose) polymerase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381420,343,041 - 20,357,904 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371420,811,773 - 20,826,063 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361419,881,613 - 19,895,903 (+)NCBINCBI36hg18NCBI36
Celera14672,919 - 687,220 (+)NCBI
Cytogenetic Map14q11.2NCBI
HuRef14933,616 - 947,915 (+)NCBIHuRef
CHM1_11420,813,199 - 20,827,472 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PARP2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1602134
Created: 2007-04-27
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.