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Gene: POLR1E (RNA polymerase I subunit E) Homo sapiens
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Symbol: POLR1E
Name: RNA polymerase I subunit E
Description: Predicted to contribute to RNA polymerase I activity. Predicted to be involved in RNA polymerase I preinitiation complex assembly; nucleolar large rRNA transcription by RNA polymerase I; and transcription elongation from RNA polymerase I promoter. Localizes to the fibrillar center and nucleoplasm; PARTICIPATES IN purine metabolic pathway; pyrimidine metabolic pathway; RNA polymerase I transcription pathway; INTERACTS WITH 2-hydroxypropanoic acid; aflatoxin B1; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DNA-directed RNA polymerase I subunit E; DNA-directed RNA polymerase I subunit RPA49; FLJ13390; FLJ13970; FLJ43482; PAF53; polymerase (RNA) I associated factor 1; polymerase (RNA) I polypeptide E; polymerase (RNA) I polypeptide E, 53kDa; polymerase (RNA) I subunit E; PRAF1; RNA polymerase I associated factor 53; RNA polymerase I subunit A49; RNA polymerase I-associated factor 1; RNA polymerase I-associated factor 53; RP11-405L18.3
Orthologs:
Mus musculus (house mouse) : Polr1e (polymerase (RNA) I polypeptide E)  MGI  Alliance
Rattus norvegicus (Norway rat) : Polr1e (RNA polymerase I subunit E)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Polr1e (RNA polymerase I subunit E)
Pan paniscus (bonobo/pygmy chimpanzee) : POLR1E (RNA polymerase I subunit E)
Canis lupus familiaris (dog) : POLR1E (RNA polymerase I subunit E)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Polr1e (RNA polymerase I subunit E)
Sus scrofa (pig) : POLR1E (RNA polymerase I subunit E)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38937,485,935 - 37,503,697 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37937,485,945 - 37,503,694 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36937,475,945 - 37,493,693 (+)NCBINCBI36hg18NCBI36
Celera937,419,179 - 37,436,922 (+)NCBI
Cytogenetic Map9p13.2NCBI
HuRef937,437,994 - 37,455,737 (+)NCBIHuRef
CHM1_1937,487,637 - 37,505,394 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on POLR1E
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1602318
Created: 2007-04-27
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.